21c Museum Hotel Louisville
5-star class on Booking.com
Restful rooms and a spa in Louisville
Live prices for your dates on Booking.com · Affiliate link
When you check availability, we take you to this hotel's page on Booking.com, where you see live rates and any current offers for your exact dates and book in one click. Prices come from Booking.com and may differ from the property's own direct rate. We never add a markup or booking fee; if you book, Booking.com may pay us a commission, at no extra cost to you. We're an independent guide, not the property; the booking completes on Booking.com.
A hotel in Louisville
Set in Louisville, Kentucky, 21c Museum Hotel Louisville is a five-star hotel. It offers a spa, a fitness center and an on-site restaurant. Room types include the Deluxe King Room - Accessible and the King Room with Roll-In Shower - Disability Access.
Who it suits
Expect a five-star hotel.
Best for
- Spa & wellness breaks
- Travelers with pets
- Business travelers
What a stay costs
Prices change by date and room. The booking site shows the total for your dates before you pay; check whether it includes taxes and local fees.
Rooms & rates
Choose from 10 room types — including the Deluxe King Room - Accessible, King Room with Roll-In Shower - Disability Access, Deluxe King Room.
Unwind at the spa
Book a treatment at the on-site spa — an easy way to relax after a day on the road or exploring the area.
The location
21c Museum Hotel Louisville is in Louisville, Kentucky.
Rooms & suites
The View availability buttons open this hotel's page on Booking.com · Affiliate link
Deluxe King Room - Accessible
40.0 m² · 1 king bed
- 1 room
- City view
- Air conditioning
- Private bathroom
- Flat-screen TV
King Room with Roll-In Shower - Disability Access
40.0 m² · 1 king bed
- 1 room
- City view
- Air conditioning
- Private bathroom
- Flat-screen TV
Deluxe King Room
31.0 m² · 1 king bed
- 1 room
- Air conditioning
- Private bathroom
- Flat-screen TV
- Coffee machine
Luxury King Room
40.0 m² · 1 king bed
- 1 room
- City view
- Air conditioning
- Private bathroom
- Flat-screen TV
Corner Suite
61.0 m² · 1 king bed
- Private suite
- City view
- Air conditioning
- Private bathroom
- Flat-screen TV
Deluxe Double Room
33.0 m² · 2 full beds
- 1 room
- Air conditioning
- Private bathroom
- Flat-screen TV
- Coffee machine
Double Room - Disability Access
42.0 m² · 2 full beds
- 1 room
- City view
- Air conditioning
- Private bathroom
- Flat-screen TV
Luxury Double Room
42.0 m² · 2 full beds
- 1 room
- City view
- Air conditioning
- Private bathroom
- Flat-screen TV
Rooftop Apartment
122.0 m² · 1 king bed
- Private suite
- Private kitchen
- Private bathroom
- Balcony
- Landmark view
Standout features
Amenities at 21c Museum Hotel Louisville
On site
- Spa
- Gym
- Wi-Fi
- Restaurant
- Bar
- 24-hour front desk
In the rooms
- Air conditioning
- Minibar
- Tea and coffee
- TV
Good to know
House rules
Check-in is from 4 pm, and check-out is by 11 am. Cancellation and prepayment terms vary by room and rate, and the booking site shows them before you pay.
Frequently asked
Does 21c Museum Hotel Louisville have a spa?
Yes, 21c Museum Hotel Louisville has a spa offering treatments and wellness facilities.
What amenities does 21c Museum Hotel Louisville offer?
21c Museum Hotel Louisville offers Non-smoking rooms, Restaurant, Fitness center, Room service, Facilities for disabled guests, Spa and wellness center, Free Wifi, Tea/Coffee Maker in All Rooms, Bar, Breakfast, Pet friendly, and Air conditioning.
What room types are available at 21c Museum Hotel Louisville?
Room options include Deluxe King Room - Accessible, King Room with Roll-In Shower - Disability Access, Deluxe King Room, Luxury King Room, Room with Balcony.
Where is 21c Museum Hotel Louisville located?
21c Museum Hotel Louisville is located in Louisville, Kentucky, at 700 West Main Street.
Hotels near 21c Museum Hotel Louisville
- Homewood Suites By Hilton Louisville Downtown· Louisville · 0.1 mi
- The Grady Hotel· Louisville · 0.1 mi
- Holiday Inn Express & Suites Downtown Louisville by IHG· Louisville · 0.1 mi
- TownePlace Suites by Marriott Louisville Downtown· Louisville · 0.2 mi
- Omni Louisville Hotel· Louisville · 0.5 mi
- Hotel Distil, Autograph Collection· Louisville · 0.5 mi
- Hilton Garden Inn Louisville Downtown· Louisville · 0.6 mi
- The Brown Hotel· Louisville · 0.8 mi
Live prices for your dates on Booking.com · Affiliate link
When you check availability, we take you to this hotel's page on Booking.com, where you see live rates and any current offers for your exact dates and book in one click. Prices come from Booking.com and may differ from the property's own direct rate. We never add a markup or booking fee; if you book, Booking.com may pay us a commission, at no extra cost to you. We're an independent guide, not the property; the booking completes on Booking.com.











